onset
Synonym discussion
Sense: noun/1
'Onset' is more formal than 'start' or 'beginning' and is especially common when something difficult or noticeable begins, such as illness, pain, winter, or war. 'Start' is the most general everyday word and fits almost any situation. 'Beginning' is also broad, but it often focuses on the first stage of a process or story rather than a sudden change. 'Outbreak' is narrower: it is used for disease, fire, fighting, or violence spreading suddenly. 'Arrival' is different again because it emphasizes the point when a person, thing, or time reaches you. Compare: 'the onset of symptoms' sounds natural, but 'the start of symptoms' is more everyday. 'The arrival of winter' focuses on winter coming, while 'the onset of winter' suggests winter beginning to be felt.
Etymology
'Onset' first appeared in English with the sense of an attack or rush forward, built from the older verb phrase 'set on'. From the idea of something striking or coming upon you, especially trouble or illness, the noun later developed the modern meaning of the point when something begins.