nuisance
Synonym discussion
Sense: noun/1
All four words describe something that troubles you, but with different shades. 'Nuisance' (the strongest of the group) suggests an ongoing or repeated problem that disrupts your daily life — a barking dog, constant noise, lost paperwork. 'Annoyance' is milder and often about a single event: a phone call during dinner is an annoyance, not a nuisance. 'Inconvenience' focuses on the effort or delay caused, not the irritation: a train strike is an inconvenience if you find another route. 'Pest' is informal and targeted at people who pester you repeatedly, like a salesperson who keeps calling. 'Bother' is the gentlest and most general: 'Sorry for the bother' works for any small trouble. If the problem is persistent and irritating enough to complain about, 'nuisance' is the right word.
Common collocations
Etymology
'Nuisance' entered English from Old French 'nuisance' (meaning harm or hurt), which came from Latin 'nocere' (to harm). Originally a legal term for injury or damage, it gradually broadened in everyday use to describe any annoying person, thing, or situation.